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Metformin is contraindicated in severe kidney disease (eGFR below 30), so baseline renal assessment is essential before initiating dual therapy

It can also be stored in the refrigerator at the temperatures mentioned above

Should one or more of these risks or uncertainties materialize, or should any of our assumptions prove incorrect, actual results may vary in material respects from those projected in these forward-looking statements

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Tirzepatide attenuates neurotoxicity by suppressing inflammation, apoptosis and restoring neurotrophin expression in an Alzheimers disease-like rat model