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Efficacy and safety of etoricoxib compared with NSAIDs in acute gout: a systematic review and a meta-analysis

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Targeting M2phenotypic TAMs reduces the polarization of macrophages toward the M2 phenotype and raises the amount of M1-TAMs, which in turn strengthens the anti-tumor immune microenvironment (38)

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This effect was not seen in a dose-related fashion, presumably through some curative mechanisms differently modified by curcumin dosage