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J Endocrinol 204:165172 Zhu HJ, Wang X, Pan H, Gong F, Zhang D, Li N, Wang L, Yang H (2014) Serum levels of the adipokine zinc-2-glycoprotein are decreased in patients with hypertension

Data were analyzed with BlueSky Statistics software version 10.3.4 (BlueSky Statistics LLC)

Reduced Food Intake: By increasing GLP-1 levels and activating vagal afferents, D-allulose helps reduce food intake, leading to weight loss

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Mechanistic studies have revealed that altered expression of iron metabolism-related proteins (including GPX4, FTH1, TfR1, and HO-1), accumulation of lipid peroxidation products, and disruption of antioxidant defense systems (particularly the Nrf2/GPX4 pathway) are central to ferroptosis progression in cardiac tissue