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Preclinical data demonstrate a restoration of intestinal barrier function upon stimulation with FXR agonists, e.g., obeticholic acid (128)

Plaintiffs claim the manufacturers failed to adequately warn patients and healthcare providers about these risks

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Additional tissue was excised with grossly negative margins

Cagrilintide is a synthetic analog of the human peptide hormone amylin, designed to explore its effects on metabolic regulation and appetite signaling in research settings

It reduced pro-inflammatory markers and improved the Pancreatic duodenal homeobox 1, glucose transporter 2, and peroxisome proliferator-activated receptors alfa and gamma