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The GC dinucleotide of MARE is critical for Maf binding, much like Nrf2/Maf heterodimer binding to ARE

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Its a molecule found in all living cells that acts as a direct precursor to NAD+ (nicotinamide adenine dinucleotide), which is an important coenzyme for cellular energy, metabolism, and DNA repair

Ann Rep Med Chem 2007

Br J Clin Pharmacol 22(2):177182

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