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DRP1 activation appears to provide a protective effect for ATC cells under KU-57788 treatment

The decision to continue, adjust, or discontinue therapy should be based on objective body composition measurements (DEXA scans, circumference measurements), achievement of fat loss goals, tolerance and side effect profile, and physician assessment of metabolic markers

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The FDAs decision was supported by data from the Phase II ROSEWOOD trial, in which the BrukinsaGazyva combo led to a 69% overall response rate (ORR) compared to 46% ORR in patients treated with Gazyva alone, according to BeiGene

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