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Nanoparticles decorated with ligands for cardiomyocyte-specific receptors enable passive targeting (e.g., the EPR effect), active targeting, and intelligent drug release in response to the pathological microenvironment (e.g., pH and enzymes), ensuring drug enrichment and localized release at the cardiac site [255, 256]

For patients with diabetes, regular monitoring of blood glucose levels and periodic measurement of hemoglobin A1c helps assess glycemic control and guide dose adjustments

The summary is provided in Tables 13

Subsequently, 100 ns of MD simulation were performed, constraining only the protein atoms

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8g,i were extracted from a different publication (their Table S2) 48