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Based on the available information, the 2024 AHA Guideline for the Primary Prevention of Stroke recommends using GLP1RAs in patients with diabetes and high cardiovascular risk or established CVD and hemoglobin A1c 7% (Class of Recommendation 1, Level of Evidence A) [36]

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It is not approved by the FDA or any other regulatory body for human or veterinary use, and nothing in this guide constitutes guidance for human administration

doi:10.3389/fcvm.2025.1477729 11

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