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Excessive dopamine, caused by inhibition of dopamine-beta-hydroxylase by Clostridia metabolites, in turn, produces oxidative species that damage neuronal Krebs cycle enzymes, neuronal mitochondria, and neuronal structural elements such as the neurofibrils

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The GLP-1 receptor agonists approved for weight loss include: Zepbound (tirzepatide), Saxenda (liraglutide), and Wegovy (semaglutide)

10.1002/hep.28709 3 ArendtB