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A Comment in @TheLancetEndo discusses the effects of GLP-1 receptor agonists on skeletal muscle mass: hubs.ly/Q02QBfSp0 GLP-1 receptor agonists, which are effective for weight loss, can cause substantial muscle loss

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The decision to use either Ppia , Hprt or Tbp was made based on the lowest variability of the housekeeper across the samples in the given tissue

CAFs-induced ECM remodeling results in increased tissue stiffness and the activation of mechanotransduction signaling pathways, such as integrin-FAK and YAP/TAZ signaling, thereby conferring increased malignancy to tumors (121)