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Nuclear factor erythroid 2 (NFE2)-related factor 2 (NRF-2) was identified as one target of SFN in murine lymphocytes, murine DCs and cancer cells ( Taken together, the existing data create a confusing picture of the effects of SFN on the intracellular redox homeostasis, which might be due to the different systems used, i.e., murine vs
doi: 10.1111/j.1365-2796.1995.tb01196.x 172
NAD + or NADPH level determines the role of ROS in infections, either protecting against invading microorganisms or causing tissue damage during the resulting excessive inflammation (Fig
