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In addition, the mRNA and protein levels of SESN2 in the PA group were lower than those in the control group, and liraglutide treatment alleviated this decrease in SESN2 expression caused by PA in a dose-dependent manner (Fig

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Indeed, in the absence of bacteria, metformin shortened lifespan implying that it is the anti-bacterial action of metformin that explains the enhancement of lifespan in C

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