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Melanin itself is not a problem

Injections should be subcutaneous (into the fatty layer under the skin) as close to the site of injury as is practical and safe

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REFERENCIAS: J Nutr

It mitigates H 2 O 2 -induced damage, enhances SOD activity [422], and activates the antioxidant response element (ARE)-Nrf2 pathway [423], thereby protecting RPE cells against elevated ROS levels