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Zafar H, Saier MH

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The core protective effects of citrulline are largely exerted through its metabolite NO, which operates via three interrelated mechanisms: first, by inhibiting the mitochondrial translocation of the fission protein Drp1, thereby preserving mitochondrial structural integrity

Decreased immune activity in the tumor microenvironment could contribute to poor prognosis and an inability to mitigate tumor growth, potentially due to immunosuppression by cancer cells or other immunosuppressive populations in the tumor microenvironment ( Our study is subject to several limitations

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