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Resting tremor, rigidity, declining balance and motor coordination, and bradykinesia, which is characterized by a creeping slowness of voluntary movement, are all movement-related symptoms of PD [17]

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Despite the thermodynamically highly favorable reverse reaction, PfGrx C88S (S 2 ) reacted very slowly with roGFP2 WT (SH) 2 most likely due to the instability and high energy of the Grx(SSR) intermediate