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If you have a lot of T4 and little T3, we know that something is blocking T4 from converting to T3 and that something is likely high reverse T3

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J Clin Endocrinol Metab (2019) 104:2892902

[2] While metformin has shown modest benefit in preventing progression to diabetes in the Diabetes Prevention Program, using tirzepatide specifically to treat prediabetes would be considered off-label and requires careful clinical judgment and shared decision-making

Further, dihexa facilitated memory consolidation and retrieval in the scopolamine-induced amnesic rat model of AD, as well as in memory compromised aged rats as measured using the Morris water maze task of spatial memory [73]