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GLP-1 medications can lead to up to 3040% of weight lost coming from lean muscle mass, whereas ESG tends to result in only about 1015% muscle loss, making it more effective at preserving lean body mass during weight reduction due to its mechanical rather than hormonal weight loss mechanism

In their stories, a new reality of the Ozempic era emerged

Front Mol Neurosci 11:394000

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Normal, reduced as well as increased insulin sensitivity have been reported in GH deficient patients (55, 56)