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The presence of extrapancreatic glucagon secretion in humans has been the focus of intense discussion for years, and even though evidence was conflicting, some investigators reported that glucagon responses after total pancreatectomy were present in animals (Sutherland and De Duve, 1948

The study population was 36.5% male, with a mean (SD) age of 76 (5) years, and 68.2% were high school graduates

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