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Common side effects Headache Lightheadedness Drowsiness Constipation Diarrhea Fatigue Serious side effects Allergic reaction (hives, swelling, breathing difficulty) Blurred or temporary vision loss Increased risk of heart rhythm problems Serotonin syndrome (when combined with other serotonergic drugs): agitation, rapid heart rate, fever, tremor, seizures Abnormal heart rhythm (QT prolongation): chest pain, dizziness, fainting, especially with electrolyte imbalances Masked signs of bowel obstruction after surgery or chemotherapy Risk in phenylketonuria with ODTs (contains aspartame) Warnings and precautions Avoid if allergic to ondansetron or other 5-HT3 antagonists Do not combine with apomorphine (risk of severe hypotension) Discuss history of long QT syndrome, heart failure, slow heart rate, liver disease, or digestive blockage Review all prescription, OTC medications, and supplements for interactions Sources Ondansetron (Rx)

In people with type 2 diabetes or specific cardiovascular risk factors, these can include improvements in insulin sensitivity, reduction in inflammatory markers, favourable effects on lipid profiles (particularly triglycerides), and potential cardiovascular benefits
doi: 10.1016/j.freeradbiomed.2020.02.016 46
Dysbiosis of gut microbiota and metabolite phenylacetylglutamine in coronary artery disease patients with stent stenosis
Neutralizes free radicals &