The standard 0.5mL weekly recommendation works for some people, but its just a starting point
Warning Signs Requiring Immediate Attention: Severe or bloody diarrhea requires urgent medical evaluation, as this may indicate gastrointestinal complications unrelated to the expected medication effects
JAMA Internal Medicine , 184(9), 10561064
doi:10.1016/0014-5793(94)01430-9
Tirzepatide causes thyroid C-cell tumors in rats, and although its unknown whether tirzepatide causes thyroid C-cell tumors in humans, it is contraindicated in patients with a personal or family history of MTC or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
In summary, our results show that semaglutide was associated with a lower risk for both incident and relapse of CUD compared to non-GLP-1 RA anti-obesity and anti-diabetes medications