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10.1016/j.tcm.2021.12.008

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People with a history of thyroid cancer, pancreatitis, or severe kidney issues should consult a doctor before taking semaglutide

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b This intervention included an initial 8-week low-calorie meal replacement diet (10001200 kcal/day), followed by a transition to a conventional hypocaloric diet (12001800 kcal/day), along with progressive physical activity goals and regular behavioural counselling over a 68-week period c All patients began treatment with open-label semaglutide, starting at 0.25 mg and gradually escalating to 2.4 mg once weekly by week 16, continuing through week 20

In my experience, many patients tolerate these symptoms better with gradual dose escalation and by taking the medication as directedon an empty stomach with water and waiting 30 minutes before eating or drinking anything else. Efficacy of semaglutide tablets The big question is: Does it work