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Rare but serious adverse events include pancreatitis and gallbladder complications, though these occur at rates below 1%

It is important to emphasise that these potential benefits are largely theoretical or extrapolated from separate studies, rather than proven through robust clinical trials of the combination

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Other potential causes include: Certain medications, including GLP-1 receptor agonists, opioid pain medications, and some antidepressants Previous stomach or abdominal surgery that affects nerves involved in digestion Neurological conditions such as Parkinson's disease or multiple sclerosis Viral infections that temporarily disrupt nerve function Autoimmune disorders that damage nerves or muscles involved in digestion Connective tissue diseases such as scleroderma In some cases, doctors can't identify a specific cause

Its essential to include TPO antibodies in a complete thyroid test because you could have high TPO levels but still show normal TSH

This can include feeling more fatigued than usual, a "foggy" feeling in the head, or a slower recovery time after physical activity