Call your doctor if that happens
Serial blood samples were collected for PK analysis at pre-specified intervals up to 672 h after the final dose (pre-dose, 4, 6, 12, 24, 36, 48, 72, 120, 168, 336, and end-of-study at 672 h)
but exogenous estrogen replacement in post-menopausal women was found to have several adverse side effects, therefore this treatment is not recommended (Rajfer et al
Hernndez-Ortiz N, Snchez-Murcia PA, Gil-Campillo C, Domenech M, Lucena-Agell D, Hortigela R
Of note, different mechanisms of action are targeted by different treatments, and exploring combinations may exploit the efficacy
Sodium, potassium, and magnesium all drop when food intake drops