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It describes any use in patients under 18 as off-label, requiring substantial medical justification and informed consent from both the provider and the family

Tirzepatide, a dual GIP/GLP-1 receptor agonist, showed even larger weight reductions in the SURMOUNT trialsup to 22% body weight loss at higher doses in non-diabetic obese individuals

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After the end of the 12-week-long experiment, the subjects from the carbohydrates group had gained on average 1.8 kg of fat and, at the same time, lost 200 g of the fat-free body mass, mainly consisting of muscle tissue

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