Obesity in pregnancy is associated with similar risks, in addition to increased chances of gestational diabetes and macrosomia (large for gestational age babies)
The timeline varies from person to person
The escalation typically started at 2 mg weekly for the first 4 weeks, then increased every four weeks in increments of 2 to 4 mg until the target research dose was reached
Additionally, adding beans to salads, choosing quinoa over rice or pasta, and supplementing with protein powders and drinks are good ways to get more protein
Gastrointestinal side effects led to treatment discontinuation in 10% of semaglutide patients versus 2% on placebo, though serious adverse events were actually less frequent with semaglutide (33.4% vs 36.4%)
It is designed for tolerance assessment, not dramatic effects