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It has also been linked to mood enhancement and emotional bonding, helping to bridge the gap between emotional intimacy and physical arousal

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Because it acts on the central nervous system, clonidine can also affect other functions, such as pain perception and withdrawal symptoms, in some cases

Because bursts of spikes induce [Ca 2+ ] i rise in any type of interneuron tested so far (Goldberg and Yuste, In weight-dependent heterosynaptic plasticity, the direction and magnitude of synaptic changes depend on the initial strength of the synapse