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It generally delivers more modest weight loss compared to GLP-1-based therapies and may be limited by gastrointestinal side effects

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However, these tumours do not exhibit the characteristic biphasic pattern of melanin-producing, keratin-positive epithelial cells, nor do they show the synaptophysin-positive neuroblast-like cells, which are key features of melanotic neuroectodermal tumour of infancy (Thompson et al., 2025)

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