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[DOI] [PMC free article] [PubMed] [Google Scholar] 162.Avella-Garcia CB, Julvez J, Fortuny J, et al

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The selectivity of the peptide is further discussed by the researchers, who suggest that senescent cells may depend more strongly on FOXO4-mediated control of p53 localization and activity, so disrupting that node might preferentially remove cells that are already operating close to an apoptotic threshold