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Semaglutide, tirzepatide, and high dose dulaglutide have been deemed to have very high likelihood of achieving adequate blood sugar control, while other GLP-1s have been deemed highly likely

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That is why the refined protocol starts at the lower dose: same weight loss, fewer problems getting there

Effect of semaglutide on weight loss and glycaemic control in patients with PraderWilli Syndrome and type 2 diabetes