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It was as if evolution had designed a molecular maintenance crew specifically for tissue repair and regeneration

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Improvement of liver enzymes was explained by the direct action of GLP-1RAs on GLP-1 receptors located on the hepatocyte that enhances weight loss, insulin sensitivity, hepatic fat oxidation, reduces denovo lipogenesis, hepatic steatosis, and alleviates oxidative stress [27,28,29,30,31,32,33,34]

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MOTS-c is a 16-amino-acid peptide encoded by mitochondrial DNA

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In addition, no parenteral formulation of these compounds is currently available, which may limit their use in the treatment of severe trauma

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