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"FDA-approved medications undergo rigorous clinical trials with thousands of participants to establish safety and efficacy, while compounded versions lack this comprehensive regulatory oversight ." FDA Guidelines, 2024 What Zepbound's Clinical Trials Actually Demonstrated The SURPASS clinical trials showed that participants taking tirzepatide achieved an average weight loss of 15% to 22.5% of their starting body weight, depending on dosage

[10] It is currently in clinical development

HMB is a secondary adjunct with mixed evidence, generally more relevant to older or untrained users

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Drugs and placebo were given for 6 months

Januvia (sitagliptin) and Jardiance (empagliflozin) are two other medications used to lower blood sugar levels in people with type 2 diabetes