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Loading regimens involve 1 mg three times weekly for two weeks, or alternate-day dosing if neurological symptoms are present

10.1093/toxsci/kfg223 80 LawsS

Precautions - Consult with your healthcare provider before starting any new supplement regimen, especially if you are pregnant, nursing, or have a medical condition

Researchers sometimes explore differences in metabolism and pharmacokinetics between genders

NMR metabolic profiling of serum identifies amino acid disturbances in chronic fatigue syndrome

It is often a sign that the supplement is either not being absorbed well or is irritating the stomach lining due to its formulation