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Cardiovascular outcomes, long-term efficacy and safety In people with T2D and established cardiovascular disease, the international guidelines for T2D recommend the use of GLP-1 RA or sodium glucose co-transporters 2 inhibitors (SGLT-2i) as first-line treatment (independent of HbA1c), based on multiple trials demonstrating their cardio-renal benefits [109]

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Glutathione plays a central role in detoxification, skin clarity, immune balance, and the bodys daily response to oxidative stress

Acta 1772 , 629644 (2007)

208 GPX4 inhibitors also induce ferroptosis and increase chemotherapy sensitivity in FZD7 + platinum-resistant ovarian cancer cells