Zepbound Active and Inactive Ingredients The active ingredient in Zepbound is tirzepatide
Tirzepatide dosing protocol Tirzepatide uses a longer, more gradual titration over 20 weeks to reach the maximum dose: Weeks 1-4: 2.5mg once weekly Weeks 5-8: 5mg once weekly Weeks 9-12: 7.5mg once weekly Weeks 13-16: 10mg once weekly Weeks 17-20: 12.5mg once weekly Week 21 onward: 15mg once weekly (maximum maintenance) Not everyone needs to reach 15mg
Avoid repeated freeze-thaw cycles and direct light exposure
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The provider reviews symptom reports, weight trends, appetite patterns, and tolerance indicators before making any adjustment
Severe Gastrointestinal Disease Tirzepatide slows stomach emptying and is not recommended for patients with severe gastrointestinal diseases, such as gastroparesis (paralysis of the stomach)