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A large majority of people see the suppression of appetite within 2-4 days, while the observable weight loss can be seen from the second or third week

Thyroid C-cell Tumors: In animal studies, Semaglutide has been associated with an increased risk of thyroid C-cell tumors

But glucagon receptor activation does far more than that

This class of drugs, encompassing Ozempic, Wegovy, Rybelsus, Trulicity, and Mounjaro, is utilized for diabetes treatment and weight management

While the long-term use of semaglutide appears safe for the general population, including those with diabetes and obesity, its long-term safety profile in hypothyroid patients requires more specific research

Individuals with a history of depression should be closely monitored for any worsening symptoms or new mental health issues