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These include: N-methyl-D-aspartate (NMDA) receptors and gamma-aminobutyric acid (GABA) receptors : NMDA receptors are linked to glutamate, a vital neurotransmitter that facilitates brain excitation, while GABA receptors are associated with inhibitory neurotransmission, playing a significant role in calming the brain

While the peripheral metabolic actions of GLP-1RAs are well established, accumulating evidence suggests that GLP-1RAs exert significant central nervous system (CNS) effects