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Funding This work was supported by a grant from Research and Technology Vice-Chancellor of Hamadan University of Medical Sciences, Hamadan, Iran (grant No

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The fluorimetric properties of SEMG enabled its chromatographic determination in spiked human plasma with acceptable sensitivity and selectivity, without using high cost and highly consuming instruments as HPLCMS

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Specifically, microglia-derived IL-1, TNF, and complement component 1q activate astrocytes via the NF-B signaling pathway, resulting in reactive astrogliosis characterized by impaired neuronal support, reduced synaptic functions, and increased neuronal vulnerability [93]