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According to Novo Nordisks Ozempic information website, the most common side effects include nausea, vomiting, diarrhea, constipation and abdominal pain

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In a Lilly-funded trial published by The Lancet, patients with type 2 diabetes who took 12 to 36 milligrams of orforglipron lost an average of 15 to 20 pounds, compared with 8 to 11 pounds for those taking 7 to 14 milligrams of Rybelsus

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Their use in this context represents off-label prescribing, which requires careful clinical justification and informed patient consent

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