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Sin embargo, dos estudios aleatorizados, doble ciego, que incluyeron 16.492 pacientes y 5.380 pacientes con DM2, el Saxagliptin Assessment of Vascular Outcomes Reported (SAVOR) 70 y el Examitation of Cardiovascular Outcomes with Alogliptin versus standar of care (EXAMINE) 71 , reportaron tasas bajas de pancreatitis aguda similares a los grupos placebo (EXAMINE, 22 y 16 pacientes) y (SAVOR, 12 y 8 pacientes)

For all these reasons, methylfolate is the better option

People might experience brief pain, redness, or swelling, or notice a small lump at the site of the shot

Here are some general scenarios that might help guide your conversation with a clinician: Oral GLP-1s may be a better fit for: People with a strong fear of needles, those who need a convenient, travel-friendly option without refrigeration, or patients like older adults looking to maintain weight loss after using injectables

GLP-1s are everywhere right now