The cannabinoid TRPA1 agonist cannabichromene inhibits nitric oxide production in macrophages and ameliorates murine colitis
partial sequence of human Body Protection Compound Sequence: H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH (GEPPPGKPADDAGLV) Synonyms: PL 14736, PLD-116 CAS Number: 137525-51-0 Molecular Formula: C 62 H 98 N 16 O 22 Molecular Weight: 1419.55 g/mol Mechanism (working): modulation of nitric oxide system, VEGFR-2 expression, and growth factor signaling supporting GI, vascular, and connective-tissue repair Regulatory status: not approved by the FDA or EMA TB-500 Compound class: synthetic N-acetylated heptapeptide
Detox Binds toxins including LPS and mycotoxins, perfect for managing Herxheimer reactions Liver Essentials Supports phase I and II liver detoxification pathways 3
Mills EL, Kelly B, Logan A, et al
(2011) 34 Suppl 2:S2517
Methods This study examined intestinal barrier function and ferroptosis-related parameters in mice with IIRI following treatment with metformin