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Ramos puts it plainly, there is the other side of the coin: in conventional medicine the direct-cause evidence is limited, and it remains unclear whether targeting permeability itself is an effective way to prevent or treat conditions like IBS

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10.1016/j.ejca.2021.01.046 [DOI] [PMC free article] [PubMed] [Google Scholar] Corti C., Giachetti P

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Abstract Estrogen-related receptors (ERR//) are ligand-responsive nuclear receptors that coordinate oxidative metabolism, mitochondrial biogenesis, and substrate selection in energetically active tissues