high-dose group: 63.1181 (mean s.e.: 97.7 12.8))
Therefore, we found that acetaminophen was metabolized to AM404, which induces analgesia by directly inhibiting the excitatory synaptic transmission via TRPV1 receptors expressed on terminals of C-fibers in the spinal dorsal horn
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Meta-regression regressed the standard mean differences against mean age, sex proportion, or mean Mini-Mental State Examination (MMSE) scores if at least 10 independent studies were included based on Cochrane recommendations