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The success of exenatide validated the therapeutic potential of GLP-1 receptor agonists and catalyzed the development of additional medications in this class

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Structural superposition of apo and DPA-bound Pa DHDPR revealed that the two conformations were highly similar, with a root-mean-square deviation of 0.54 (over 244 C atoms) (Fig

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Previously, GLP-1s were only being prescribed to those who were overweight or obese and had other qualifying medical conditions

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