They are naturally rich in glutathione
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Journal of Medical Genetics , 2003;40:619-625
Besides acting as a primary S phase PARP target and subsequently a Sororin cofactor during sister chromatid cohesion, RSMC has been recently reported to bind 28S rRNA and play a critical role in ribosome biogenesis (Zhang et al, 2023b)
However, it is likely that the high serum ferritin observed in other cancers may be a generic cancer characteristic that is applicable to all brain cancers
Modified NAD and glutathione metabolism is associated with a number of diseases, but no data exist of how specific pathology is shifting blood redox profile
