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Accelerated atherosclerosis in patients with SLEmechanisms and management

Improving access to DHA-rich foods through context-appropriate dietary strategies, supplementation, or food fortification may contribute to reducing income-related disparities in cardiometabolic, neurocognitive, and inflammation-related health outcomes

Compound 28 exhibited an IC 50 value of 7.5 nM, compared to febuxostat, with an IC 50 value of 7.8 nM, both of which strongly inhibit the enzyme

The reactions were allowed to incubate in the dark at 37 C for 30 min, during which fluorescence was measured in a SpectraMax iD3 Multi-Mode Microplate Reader (Molecular Devices, San Jose, CA, USA) using excitation in the range of 530560 nm and emission detection at 590 nm