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& Gill, J

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however, its application is significantly constrained by life-threatening cardiotoxic effects and the potential for developing cardiomyopathy

Evidence: A crossover study in healthy Italian volunteers compared a single high oral dose of SAG (3.5 g as powder dissolved in water) with the same dose of regular L-glutathione (3.5 g as capsules)

[6] Perry G, Nunomura A, Hirai K, Zhu XW, Perez M, Avila J, Castellani RJ, Atwood CS, Aliev G, Sayre LM, Takeda A, Smith MA (2002) Is oxidative damage the fundamental pathogenic mechanism of Alzheimers and other neurode- generative diseases