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Khemis et al., 2007

This indicated that, along with an overall decrease in TG synthesis, specific pathways/enzymes involved in polyunsaturated fatty acid (PUFA) synthesis may be stimulated in the livers of KO mice

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GLP-1 RAs are chronic medications for long-term use

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By selectively inducing ferroptosis in tumor cells while protecting normal tissues, it is possible to exploit this vulnerability for therapeutic benefit