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Multiple investigational therapies ranging from tolerogenic to immunological approaches are in the pipeline, and several drug candidates have entered phase II/III clinical trials

Inhibition of KEAP1 by RTA 408 disinhibits the antioxidant transcription factor nrf2 and has neuroprotective and seizure reducing effects in the kainic model of TLE (Shekh-Ahmad et al., 2018)

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To view a copy of this license, visit About this article Cite this article Martn, A.R., Patel, J.M., Zlotnick, H.M

Unlike many peptides that degrade quickly in acidic environments, BPC-157 is notable for its stability in gastric conditions, which led researchers to study its potential effects on the digestive system