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4F, in si-EAAT3 and si-P65 cells, despite being in a state of oxidative stress, TEM revealed that mitochondrial morphology remained largely normal, with only a slight increase in electron density and occasional mitochondrial membrane rupture, which appeared to be within the cells adaptive capacity

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In a study on both mice and humans, researchers found that pre-exercise glutathione administration improved lipid metabolism and acidification in the skeletal muscle of the subjects, resulting in less muscle fatigue [9]