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Later, the [Ca2+cyt] elevation activates the calcium sensor activated via phosphorylation by mitogen-activated protein kinase kinases (MAPKKs)

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Enhanced phosphorylation of MAPKs by NE promotes TNF- production by macrophage through adrenergic receptor

Inclusion criteria included that the participants have ASD and be within 35 years of age at the start of, and during the trial period